Artropatía de Charcot en el paciente diabético. Revisión de Conceptos Actuales

Autores/as

  • José Fernando Muñoz-De-La-Calle Hospital General de Medellín Luz Castro de Gutiérrez
  • Jordi Viadé-Julià Hospital Universitario Germans Trias i Pujol. Badalona, España

DOI:

https://doi.org/10.1016/j.rccot.2020.04.013

Palabras clave:

diabetes mellitus, artropatía de Charcot, pie diabético, tratamiento quirúrgico, amputación, química sanguínea

Resumen

La Neuroartropatía de Charcot (NA), a pesar de ser documentada desde hace cerca 120 años, es apenas en las dos últimas décadas que su comprensión viene en incremento, dado el entendimiento en la causalidad y la relación proporcional con el incremento de la prevalencia de diabetes mellitus. Ello genera retos importantes en su tratamiento enfocado actualmente en la preservación a priori de la extremidad dada la relación de la amputación con incremento del gasto cardiaco, la perdida de calidad de vida, depresión, infección a niveles más elevados de la extremidad, incremento de costos a largo plazo para el sistema sanitario, pérdida de calidad de vida y la asociación elevada con mortalidad a 5 años incluso mayores a neoplasias tan prevalentes como de mama y colon. Aunque el diagnóstico es predominantemente clínico, el apoyo en química sanguínea, en imágenes convencionales y/o de resonancia magnética, PET/TC ayudan a diferenciar el proceso per se y la posible relación con infección subyacente. El advenimiento de cirugías reconstructivas y la compresión técnica de ellas vienen dando pistas para conseguir el objetivo de preservar la extremidad y rehabilitar a los pacientes diabético. Se hace una revisión de la literatura más reciente.
Nivel de evidencia: IV

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Biografía del autor/a

José Fernando Muñoz-De-La-Calle, Hospital General de Medellín Luz Castro de Gutiérrez

Ortopedista y Traumatólogo Universidad Nacional de Colombia, Hospital General de Medellín Luz Castro de Gutiérrez.

Jordi Viadé-Julià, Hospital Universitario Germans Trias i Pujol. Badalona, España

Responsable unidad Pie Diabético. Servicio de Endocrinología y Nutrición. Hospital Universitario Germans Trias i Pujol. Badalona, España.

Referencias bibliográficas

Blume P, Sumpio B, Schmidt B, Donegan R. Charcot Neuroarthropathy of the Foot and Ankle. Diagnosis and Management Strategies Clin Podiatr Med Surg. 2014;31:151-72. https://doi.org/10.1016/j.cpm.2013.09.007

Papanas N, Maltezos E. Etiology, pathophysiology and classifications of the diabetic Charcot foot. Diabet Foot Ankle. 2013;4:208-72. https://doi.org/10.3402/dfa.v4i0.20872

Brandão R, Weber J, Larson D, Prissel M, Bull P, Berlet G, Hyer C. New Fixation Methods for the Treatment of the Diabetic Foot Beaming, External Fixation, and Beyond. Clin Podiatr Med Surg. 2018;35:63-76. https://doi.org/10.1016/j.cpm.2017.08.001

Armstrong DG, Wrobel J, Robbins JM. Guest editorial: are diabetes-related wounds and amputations worse than cancer. Int Wound J. 2007;4:286-7. https://doi.org/10.1111/j.1742-481X.2007.00392.x

Miller R. Neuropathic Minimally Invasive Surgeries (NEMESIS): Percutaneous Diabetic Foot Surgery and Reconstruction. Foot Ankle Clin N Am. 2016;21:595-627. https://doi.org/10.1016/j.fcl.2016.04.012

Zimmet PZ. Kelly West Lecture 1991. Challenges in diabetes epidemiology--west to the rest. Diabetes Care. 1992;15:232-52. https://doi.org/10.2337/diacare.15.2.232

Rogers LC, Frykberg RG, Armstrong DG, et al. The Charcot foot. J Am Podiatr Med Assoc. 2011;101:437-46. https://doi.org/10.7547/1010437

Lavery LA, Armstrong DG, Wunderlich RP, et al. Risk factors for foot infections in individuals with diabetes. Diabetes Care. 2006;29:1288-93. https://doi.org/10.2337/dc05-2425

NICE--Diabetic foot problems: preventions and management. NICE Guideline. 2015.

McCabe CJ, Stevenson RC, Dolan AM. Evaluation of a diabetic foot screening and protection programme. Diabet Med. 1998;15:80-4. https://doi.org/10.1002/(SICI)1096-9136(199801)15:1<80::AID-DIA517>3.0.CO;2-K

Pinzur MS. Neutral ring fixation for high-risk nonplantigrade Charcot midfoot deformity. Foot Ankle Int. 2007;28:961-6. https://doi.org/10.3113/FAI.2007.0961

Schofield CJ, Libby G, Brennan GM, et al. Mortality and hospitalization in patients after amputation: a comparison between patients with and without diabetes. Diabetes Care. 2006;29:2252-6. https://doi.org/10.2337/dc06-0926

Reiber GE, Vileikyte L, Boyko EJ, et al. Causal pathways for incident lowerextremity ulcers in patients with diabetes from two settings. Diabetes Care. 1999;22:157-62. https://doi.org/10.2337/diacare.22.1.157

Madan SS, Pai DR. Charcot neuroarthropathy of the foot and ankle. Orthop Surg. 2013;5:86-93. https://doi.org/10.1111/os.12032

Brem H, Tomic-Canic M. Cellular and molecular basis of wound healing in diabetes. J Clin Invest. 2007;117:1219-22. https://doi.org/10.1172/JCI32169

Nazimek-Siewniak B, Moczulski D, Grzeszczak W. Risk of macrovascular and microvascular complications in type 2 diabetes: results of longitudinal study design. J Diabet Complications. 2002;16:271-6. https://doi.org/10.1016/S1056-8727(01)00184-2

Newman JH. Non-infective disease of the diabetic foot. J Bone Joint Surg Br. 1981;63:593-6. https://doi.org/10.1302/0301-620X.63B4.7298692

Eichenholtz SN. Charcot joints. Springfield (IL): Charles C Thomas; 1966.

Shibata T, Tada K, Hashizume C. The result of arthrodesis of the ankle for leprotic neuroarthropathy. J Bone Joint Surg Am. 1990;72:749-56. https://doi.org/10.2106/00004623-199072050-00016

Jeffcoate WJ. Review Charcot neuro-osteoarthropathy. Diabetes Metab Res Rev. 2008;24:S62-5. https://doi.org/10.1002/dmrr.837

Eichenholtz SN. Charcot joints. Springfield (IL): Charles C Thomas; 1966.

Wukich DK, Raspovic KM, Hobizal KB, et al. Radiographic analysis of diabetic midfoot Charcot neuroarthropathy with and without midfoot ulceration. Foot Ankle Int. 2014;35:1108-15. https://doi.org/10.1177/1071100714547218

Hastings M, Johnson J, Strube M, Hildebolt C, Bohnert K, Prior F, Sinacore D. Progression of Foot Deformity in Charcot Neuropathic Osteoarthropathy. J Bone Joint Surg Am. 2013;95:1206-13. https://doi.org/10.2106/JBJS.L.00250

Rogers LC, Frykberg RG, Armstrong DG, et al. The Charcot foot in diabetes. Diabetes Care. 2011;34:2123-9. https://doi.org/10.2337/dc11-0844

Dalla Paola L. Confronting a dramatic situation: the Charcot foot complicated by osteomyelitis. Int J Low Extrem Wounds. 2014;13:247-62. https://doi.org/10.1177/1534734614545875

Tan PL, Teh J. MRI of the diabetic foot: differentiation of infection from neuropathic change. Br J Radiol. 2007;80:939-48. https://doi.org/10.1259/bjr/30036666

Petrova N, Edmonds E. Conservative and Pharmacologic Treatments for the Diabetic Charcot Foot. Clin Podiatr Med Surg. 2017;34:15-24. https://doi.org/10.1016/j.cpm.2016.07.003

Pinzur M. Surgical versus accommodative treatment for Charcot arthropathy of the midfoot. Foot Ankle Int. 2004;25:545-9. https://doi.org/10.1177/107110070402500806

Papanas N, Maltezos E. Etiology, pathophysiology and classifications of the diabetic Charcot foot. Diabet Foot Ankle. 2013;4:208-72. https://doi.org/10.3402/dfa.v4i0.20872

Saltzman CL, Hagy ML, Zimmerman B, et al. How effective is intensive nonoperative initial treatment of patients with diabetes and Charcot arthropathy of the feet? Clin Orthop Relat Res. 2005;435:185-90. https://doi.org/10.1097/00003086-200506000-00026

Burns P, Monaco S. Revisional Surgery of the Diabetic Charcot Foot and Ankle. Clin Podiatr Med Surg. 2017;34:77-92. https://doi.org/10.1016/j.cpm.2016.07.009

Wukich DK, Crim BE, Frykberg RG, et al. Neuropathy and poorly controlled diabetes increase the rate of surgical site infection after foot and ankle surgery. J Bone Joint Surg Am. 2014;96:832-9. https://doi.org/10.2106/JBJS.L.01302

Pinzur MS, Sage R, Stuck R, et al. Transcutaneous oxygen as a predictor of wound healing in amputations of the foot and ankle. Foot Ankle Int. 1992;13:271-2. https://doi.org/10.1177/107110079201300507

Waters RL, Perry J, Antonelli D, et al. Energy cost of walking amputees: the influence of level of amputation. J Bone Joint Surg Am. 1976;58:42-6. https://doi.org/10.2106/00004623-197658010-00007

Sammarco VJ. Superconstructs in the treatment of Charcot foot deformity: plantar plating, locked plating, and axial screw fixation. Foot Ankle Clin. 2009;14:393-407. https://doi.org/10.1016/j.fcl.2009.04.004

Schon LC, Easley ME, Cohen I, et al. The acquired midtarsus deformity classification system--interobserver reliability and intraobserver reproducibility. Foot Ankle Int. 2002;23:30-6. https://doi.org/10.1177/107110070202300106

Zgonis T, Stapleton JJ, Roukis TS. A stepwise approach to the surgical management of severe diabetic foot infections. Foot Ankle Spec. 2008;1:46-53. https://doi.org/10.1177/1938640007312316.

Bevan WP, Tomlinson MP. Radiographic measures as a predictor of ulcer formation in diabetic Charcot midfoot. Foot Ankle Int. 2008;29:568-73. https://doi.org/10.3113/FAI.2008.0568

J Short D, Zgonis T. Circular External Fixation as a Primary or Adjunctive Therapy forthe Podoplastic Approach ofthe Diabetic Charcot Foot. Clin Podiatr Med Surg. 2017;34:93-8. https://doi.org/10.1016/j.cpm.2016.07.010

Sammarco GJ, Conti SF. Surgicaltreatment of neuroarthropathic foot deformity. Foot Ankle Int. 1998;19:102-9. https://doi.org/10.1177/107110079801900209

Mittlmeier T, Klaue K, Haar P, et al. Should one consider primary surgical reconstruction in Charcot arthropathy of the feet? Clin Orthop Relat Res. 2010;468:1002-11. https://doi.org/10.1007/s11999-009-0972-x

Tamir E, McLaren AM, Gadgil A, et al. Outpatient percutaneous flexor tenotomies for management of diabetic claw toe deformities with ulcers: a preliminary report. Can J Surg. 2008;51: 41-4.

Chen L, Greisberg J. Achilles lengthening procedures. Foot Ankle Clin. 2009;14:627-37. https://doi.org/10.1016/j.fcl.2009.08.002

Ramanujam C, Zgonis T. Surgical Correction of the Achilles Tendon for Diabetic Foot Ulcerations and Charcot Neuroarthropathy. Clin Podiatr Med Surg. 2017;34:275-80. https://doi.org/10.1016/j.cpm.2016.10.013

Lowery NJ, Woods JB, Armstrong DG, et al. Surgical management of Charcot neuroarthropathy of the foot and ankle: a systematic review. Foot Ankle Int. 2012;33:113-21. https://doi.org/10.3113/FAI.2012.0113

Grant WP, Garcia-Lavin S, Sabo R. Beaming the columns for Charcot diabetic foot reconstruction: a retrospective analysis. J Foot Ankle Surg. 2011;50:182-9. https://doi.org/10.1053/j.jfas.2010.12.002

Latt LD, Glisson RR, Adams SB Jr, et al. Biomechanical comparison of external fixation and compression screws for transverse tarsal joint arthrodesis. Foot Ankle Int. 2015;36:1235-42. https://doi.org/10.1177/1071100715589083

Lamm BM, Siddiqui NA, Nair AK, et al. Intramedullary foot fixation for midfoot Charcot neuroarthropathy. J Foot Ankle Surg. 2012;51:531-6. https://doi.org/10.1053/j.jfas.2012.04.021

Pinzur MS, Gil J, Belmares J. Treatment of osteomyelitis in Charcot foot with single-stage resection of infection, correction of deformity, and maintenance with ring fixation. Foot Ankle Int. 2012;33:1069-74. https://doi.org/10.3113/FAI.2012.1069

Fong Mak M, Stern R, Assal M. Masquelet Technique for Midfoot Reconstruction Following Osteomyelitis in Charcot Diabetic Neuropathy A Case Report. JBJS Case Connect. 2015;5:e28. https://doi.org/10.2106/JBJS.CC.N.00112

Ogut T, Yontar NS. Surgical treatment options for the diabetic Charcot hindfoot and ankle deformity. Clin Podiatr Med Surg. 2017;34:53-67. https://doi.org/10.1016/j.cpm.2016.07.007

Ettinger S, Plaass C, Claassen L, et al. Surgical management of Charcot deformity for the foot and ankle-radiologic outcome after internal/external fixation. J Foot Ankle Surg. 2016;55:522-8. https://doi.org/10.1053/j.jfas.2015.12.008

Firth GB, McMullan M, Chin T, et al. Lengthening of the gastrocnemius-soleus complex: an anatomical and biomechanical study in human cadavers. J Bone Joint Surg Am. 2013;95:1489-96. https://doi.org/10.2106/JBJS.K.01638

Hsu R, VanValkenburg S, Tanriover A, DiGiovanni C. Surgical Techniques of Gastrocnemius Lengthening. Foot Ankle Clin N Am. 2014;19:745-65. https://doi.org/10.1016/j.fcl.2014.08.007

Kim P, Steinberg J, Kikuchi M, Attinger C. Tibialis Anterior Tendon Lengthening: Adjunctive Treatment of Plantar Lateral Column Diabetic Foot Ulcers. The Journal of Foot & Ankle Surgery. 2015;54:686-91. https://doi.org/10.1053/j.jfas.2015.04.006

Chen L, Greisberg J. Achilles lengthening procedures. Foot Ankle Clin. 2009;14:627-37. https://doi.org/10.1016/j.fcl.2009.08.002

Mallory D, Dikis A, Highlander P, et al. Panfoot Arthrodesis: A Novel Technique for Management of Challenging Midfoot Charcot Deformity. American College of Foot and Ankle Surgeons Annual Scientific Meeting. Phoenix (AZ). 2015. February 19-22.

Pope E, Takemoto RC, Kummer FJ, et al. Midfoot fusion: a biomechanical comparison of plantar planting vs intramedullary screws. Foot Ankle Int. 2015;34:409-13. https://doi.org/10.1177/1071100712464210

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Publicado

2020-05-28

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1.
Muñoz-De-La-Calle JF, Viadé-Julià J. Artropatía de Charcot en el paciente diabético. Revisión de Conceptos Actuales. Rev. colomb. ortop traumatol. [Internet]. 28 de mayo de 2020 [citado 17 de mayo de 2024];34(1):5-15. Disponible en: https://revistasccot.org/index.php/rccot/article/view/229

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